Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 57. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2169Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI98% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2170Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI90% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2171Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI70% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2172Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI30% cell survival after day 4NoNoNA No responseNANANANA22059912
OV_2173Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI10% cell survival after day 5NoNoNA No responseNANANANA22059912
OV_2174Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI85% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2175Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI70% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2176Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI30% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2177Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI10% cell survival after day 4NoNoNA No responseNANANANA22059912
OV_2178Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-21.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOIAll cells was dead after day 5NoNoNA No responseNANANANA22059912
OV_2179Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI90% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2180Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI70% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2181Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI20% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2182Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI5% cell survival after day 4NoNoNA No responseNANANANA22059912
OV_2183Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOIAll cells was dead after day 5NoNoNA No responseNANANANA22059912
OV_2184Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI80% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2185Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI30% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2186Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI10% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2187Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOIAll cells was dead after day 4NoNoNA No responseNANANANA22059912
OV_2188Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOIAll cells was dead after day 5NoNoNA No responseNANANANA22059912
OV_2189Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI98% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2190Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI85% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2191Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI70% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2192Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI30% cell survival after day 4NoNoNA No responseNANANANA22059912
OV_2193Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI20% cell survival after day 5NoNoNA No responseNANANANA22059912
OV_2194Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI85% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2195Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI70% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2196Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI30% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2197Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI10% cell survival after day 4NoNoNA No responseNANANANA22059912
OV_2198Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineNPEC2/Bm11.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOIAll cells was dead after day 5NoNoNA No responseNANANANA22059912
OV_2199Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI95% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2200Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI95% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2201Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI95% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2202Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI85% cell survival after day 4NoNoNA No responseNANANANA22059912
OV_2203Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.01 MOI80% cell survival after day 5NoNoNA No responseNANANANA22059912
OV_2204Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI78% cell survival after day 1NoNoNA No responseNANANANA22059912
OV_2205Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI65% cell survival after day 2NoNoNA No responseNANANANA22059912
OV_2206Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI45% cell survival after day 3NoNoNA No responseNANANANA22059912
OV_2207Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI30% cell survival after day 4NoNoNA No responseNANANANA22059912
OV_2208Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoDr. George SW Tsao Center, Hong Komg universityHuman nasopharyngeal carcinoma cell lineNP691.0E+5 cells per wellNAX-gal staining and MTT assay0.1 MOI20% cell survival after day 5NoNoNA No responseNANANANA22059912
OV_2209Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineCNE-2NANANANANABalb/c nude mice xenograft for CNE-2 cell line (1.0E+6 × 10⁶ cells)2.0E+7 pfuNA Virus treated mice shows complete regression in tumor and exhibit longer survival timeIntratumoralNANANA22059912
OV_2210Herpes simplex virusHSV-1-G47-deltaDNAHerpesviridaeMutant for Gamma34.5, ICP6 and alpha47 geneYesNoNoHongkong universityHuman nasopharyngeal carcinoma cell lineSUNE-1NANANANANABalb/c nude mice xenograft for SUNE-1 cell line (5.0E+5 × 10⁵ cells)2.0E+7 pfuNA Virus treated mice shows complete regression in tumor and exhibit longer survival timeIntratumoralNANANA22059912
OV_3665Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHK-15000 cells per wellNAMTT assay1 MOI70% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3666Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHK-15000 cells per wellNAMTT assay1 MOI5% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3667Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHONE-15000 cells per wellNAMTT assay1 MOI30% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3668Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHONE-15000 cells per wellNAMTT assay1 MOI20% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3681Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHK-15000 cells per wellNAMTT assay1 MOI75% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3682Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHK-15000 cells per wellNAMTT assay1 MOIComplete cell death after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3683Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHONE-15000 cells per wellNAMTT assay1 MOI80% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3684Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman nasopharyngeal cell lineHONE-15000 cells per wellNAMTT assay1 MOI75% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3697Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman nasopharyngeal cell lineHK-15000 cells per wellNAMTT assay1 MOI50% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3698Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman nasopharyngeal cell lineHK-15000 cells per wellNAMTT assay1 MOIComplete cell death after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3699Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman nasopharyngeal cell lineHONE-15000 cells per wellNAMTT assay1 MOI50% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3700Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman nasopharyngeal cell lineHONE-15000 cells per wellNAMTT assay1 MOIComplete cell death after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_4281AlphavirusM1RNATogaviridaeNoneYesNoNoSICBHuman nasopharyngeal carcinomaCNE-24000 cells per wellNAMTT assay10 pfu24.5 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4295AlphavirusM1RNATogaviridaeNoneYesNoNoSICBHuman nasopharyngeal carcinomaCNE-14000 cells per wellNAMTT assay10 pfu48.2 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4310AlphavirusM1RNATogaviridaeNoneYesNoNoSICBHuman nasopharyngeal carcinomaHNE-14000 cells per wellNAMTT assay10 pfu76.5 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347